Fill in the blanks: 1,1,2,3,7,16,65_ ,4546,……

Fill in the blanks: 1,1,2,3,7,16,65_ ,4546,……

three hundred and twenty-one
The second number of = = = = the third number of squares
16^2+65=321

Find the rule: 2 → 3 65 → 1 → 1 7 → 16=
1→1→2→3→7→16→65→？

The square of the first number + the second number = the third number 2 = 1 ^ 2 + 1 3 = 1 ^ 2 + 2 7 = 2 ^ 2 + 3 16 = 3 ^ 2 + 7 65 = 7 ^ 2 + 16 16 ^ 2 + 65 = 321, so it's 321

Sequence relations: - 22, - 17, - 12, (), - 23

The title should be: - 22, - 17, - 12, (), - 2,3. There is a comma missing, which is very different. I do it by adding a comma
-22,-17,-12,(-7),-2,3