There are five nonzero rational numbers A, B, C, D, E. If A-B >0, AB <0,ABC>0, CD >0, DE >0, please judge the positive and negative values of the five rational numbers.

There are five nonzero rational numbers A, B, C, D, E. If A-B >0, AB <0,ABC>0, CD >0, DE >0, please judge the positive and negative values of the five rational numbers.

A-B >0 then A > B
AB <0 means A and B are different
Then A >0 B <0
ABC >0 because AB <0 indicates C <0
CD >0 because C <0 indicates D <0
DE >0 because D <0 indicates E <0
So A is a positive number B negative number C negative number D negative number E negative number

What is the value of (-5)#(+4)#(-3) if the newly defined operation #:a# b=ab+1 for any nonzero rational number a, b

(-5)#(+4)=(-5)×(+4)+1=-19
(-19)#(-3)=(-19)×(-3)+1=58