How many of the 52 playing cards can guarantee that at least one of them is two (explain the reason)

How many of the 52 playing cards can guarantee that at least one of them is two (explain the reason)

49
Suppose that four of the 52 cards are two. Reverse thinking, take out the four two, the remaining 48 cards can not guarantee that there are two. In order to guarantee that there must be two, you must touch 48 cards and then touch one two. Therefore, you must touch at least 49 cards to ensure that at least one of them is two